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Normothermic Regional Perfusion
Strata Critical is a national leader in Normothermic Regional Perfusion (NRP), delivering thousands of successful cases, including A-NRP and complex TA‑NRP, with consistently strong utilization and organ quality outcomes. Our dedicated NRP perfusionists and surgeons bring deep expertise across TA‑NRP, ECMO‑based NRP, and machine perfusion integration, ensuring stability, precision, and high‑quality recoveries in every donor scenario.
We support all major preservation platforms, including TransMedics OCS, OrganOx Metra, Paragonix, ORS LifePort, and emerging technologies, giving OPOs a device‑agnostic partner capable of adapting to any clinical environment.
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650+
1,800+
11
24/7
Adult and Pediatric NRP
TA-NRP and A-NRP
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More About Our Comprehensive NRP Services
- Certified Clinical Perfusionists: Our experienced perfusionists are NRP experts, providing unmatched care and precision.
- Cutting-Edge Equipment: We supply the latest heart-lung/ECMO equipment available to facilitate NRP procedures.
- Disposable Supplies: All necessary disposables are provided to streamline the NRP process.
- Pharmaceutical Support: Access to essential medications to support the perfusion process.
- Education and Training: Strata Critical offers tailored education and training to ensure your team's proficiency in NRP procedures.
- Point-of-Care Testing: We employ advanced point-of-care testing for real-time blood gas analysis, activated clotting time (ACT) monitoring, and lactate level assessment. This ensures that vital parameters are closely monitored and managed during NRP procedures, contributing to improved organ preservation.
- Policy and Procedure Development: We assist in developing custom protocols and procedures to align with your institution's needs.
Addressing the Organ Shortage Crisis with NRP
The field of transplant medicine is rapidly advancing to combat the severe organ shortagecrisis. With increasing congressional scrutiny and the demand for more efficient organ use, there's a growing urgency to optimize the utilization of transplantable organs obtained from donors who have been declared dead by circulatory criteria.
Unlike organs obtained from living or brain-dead donors, those procured from donations after circulatory death (DCD) often face challenges such as hypoxic-ischemic injury. This injury occurs because DCD organs cannot be removed until the donor has been declared dead, typically in the United States after being pulseless for 5 minutes.
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The Benefits of Normothermic Regional Perfusion
Normothermic Regional Perfusion (NRP) represents a groundbreaking approach to organ preservation and assessment. Unlike traditional "ex-vivo" perfusion, NRP utilizes advanced extracorporeal membrane oxygenation (ECMO) or cardiopulmonary bypass technology to restore circulation and perfuse DCD donor organs before recovery. The advantages of NRP are significant:
- Reduced Warm Ischemia Time: NRP dramatically reduces warm ischemia time, a critical factor in organ transplant success.
- Enhanced Organ Assessment: NRP enables thorough assessment of DCD donor organs, ensuring optimal transplant outcomes.
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Need NRP Support?
Our team is available to discuss coverage models and upcoming needs.
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